Natural Stacks Review: My Honest Opinion

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Nootropics dietary supplements have been gaining extra reputation lately. Particularly with the elevated curiosity within the mind and biohacking. Since they’ve turn into so common, there are actually numerous manufacturers on the market, however they’re not all created equal.

Pure Stacks is one nootropics model that I wished to check out. I attempted a number of of their merchandise and wished to share some sincere ideas about how they affected me. However first, let’s cowl the fundamentals of nootropics.

What Are Nootropics and Why Use Them? 

Nootropics (additionally “good medication” or cognitive enhancers) are substances that have an effect on the mind indirectly. They might defend the mind or improve cognitive efficiency. Nootropics may also enhance the effectivity of neurotransmitter manufacturing and the way they act on mind cells. 

What Is Pure Stacks?

Pure Stacks is a high quality complement firm that focuses on higher mind well being. The thought is to “stack” your dietary supplements so that you’ve got one thing custom-made to your wants. As an alternative of making an attempt to get every little thing we want multi functional complement (which isn’t going to occur).

You will get their pre-bundled stacks for particular well being wants, like temper, mind meals, and psychological efficiency, or create your personal bundle of dietary supplements. They provide merchandise individually, however stacking them will get you one of the best low cost. Extra on that on the finish of this evaluation, however for now let me inform you how Pure Stacks labored for me.

NEUROFUEL™ by Pure Stacks 

NEUROFUEL™ is Pure Stacks’ authentic complement. It was initially referred to as CILTEP, an acronym for “Chemically-Induced Lengthy Time period Potentiation.” Don’t let the title idiot you although! Pure Stacks is made with all-natural substances. 

The “chemically-induced” half refers to the way it will increase biochemical features within the mind. Neurofuel does this via a number of completely different actions:

  1. Inhibiting PDE enzymes
  2. Rising cAMP ranges

#1 Inhibiting Phosphodiesterase (PDE) Enzymes 

PDE enzymes would in any other case break down one thing referred to as cyclic adenosine monophosphate (cAMP). Blocking PDEs has a constructive impact on reminiscence. Blocking PDE4, particularly, is helpful for neurodegenerative ailments like Alzheimer’s and Parkinson’s. It could additionally enhance wakefulness and focus. Some pure PDE4 inhibitors embody Artichoke extract, luteolin, and an herb referred to as Kanna. 

#2 Rising cAMP Ranges (Cyclic adenosine monophosphate)

cAMP naturally amps up the actions of hormones and neurotransmitters. These embody epinephrine (adrenalin) and acetylcholine. Whereas blocking PDE helps enhance cAMP ranges, Neurostack’s substances additionally immediately enhance them. That is because of the herb, Coleus forskohlii, with its lively compound, forskolin. Neurofuel makes use of artichoke extract to additionally assist block PDE. 

By blocking PDE and rising cAMP, it has a strong impact on a course of often called Lengthy Time period Potentiation. Scientists consider this course of is the important thing to studying and retaining new data. 

Neurofuel additionally comprises an amino acid, acetyl-L-carnitine (ALCAR). This amino acid crosses the blood-brain barrier to assist mitochondria and enhance power. ALCAR additionally helps battle mind fog and fatigue.

The L-phenylalanine within the components helps construct dopamine for focus and motivation. And the lively type of vitamin B6 lowers emotions of stress and helps create calm, targeted power. You possibly can see why Neurofuel is so efficient for readability, focus, reminiscence, and motivation! 

My Expertise With NEUROFUEL™

I bought to attempt each their capsule and their lemonade drink packets. I might really feel each merchandise inside half an hour. Regardless of a number of quick nights of sleep, after taking Neurofuel, I felt targeted, clear-headed, and able to be productive. It was an incredible method to begin the day. 

I particularly favored the lemonade packets as a result of it’s a good way to verify I begin the day with a glass of water on an empty abdomen. They combine simply with out settling to the underside of the glass they usually style nice! 

The flavour comes from crystallized lemon extract, with some stevia and natural monk fruit for sweetness. No humorous enterprise right here. 


 Serotonin (aka the “pleased molecule”) is a neurotransmitter that helps us really feel calm, targeted, and optimistic. Scientists have discovered that 95% of the physique’s serotonin is produced within the intestine. Once we feed our physique the suitable vitamins, we are able to enhance serotonin manufacturing within the intestine. 

Pure Stacks’ Serotonin Mind Meals has the vitamins wanted for optimum serotonin manufacturing.

  • Rhodiola Rosea – Helps stress aid, combats fatigue and burnout, uplifts temper, and boosts power and efficiency.
  • L-Tryptophan – An important amino acid that reinforces temper, improves cognitive talents, and promotes constructive behaviors. The intestine converts tryptophan to serotonin.
  • Vitamin B3 – Will increase blood stream within the mind, helps produce power, and protects the physique towards free radical injury. 
  • Magnesium Glycinate – Helps relieve stress, improves consideration, upgrades sleep high quality, and sharpens reminiscence.
  • Zinc Glycinate – Helps a wholesome immune system, and helps enhance serotonin within the mind. 

Wholesome serotonin ranges are linked with:

  • Optimistic social habits
  • Resilience within the face of stress
  • Optimism
  • Humor
  • Cognitive flexibility
  • Higher psychological well being typically

My Expertise With Pure Stacks’ Serotonin Mind Meals™ Complement

I took the serotonin complement principally within the night, but in addition in the course of the day on some overcast days. I might undoubtedly really feel an impact; usually, a way of balanced calm and a greater outlook. I feel it helped me sleep slightly higher after I took it within the night. 

SMART CAFFEINE® by Pure Stacks

Generally you simply want slightly further hit of caffeine… however with out the jitters. Pure Stacks’ Sensible Caffeine combines caffeine with the calming amino acid, L-theanine for a balanced power enhance. L-theanine is the balancing amino acid discovered that comes from inexperienced tea. 

The 2 work collectively to enhance consideration and application, reminiscence, and cognitive functioning. It even helps us have the flexibility to disregard distractions. What mama doesn’t want that!

A 2008 research discovered  L-theanine and caffeine labored synergistically to enhance pace and accuracy when multitasking. The mixture additionally decreased research individuals’ susceptibility to distraction throughout a reminiscence job. Collectively they assist enhance efficiency when we have to actually use our brainpower.

My Expertise With Pure Stacks’ Caffeine Complement

I might undoubtedly really feel the caffeine, and it didn’t take lengthy for it to kick in. I took it about mid-morning after I was sitting at my laptop computer, typing an article, and was starting to really feel a bit sleepy. It helped deliver again my focus rapidly and I felt way more productive for the remainder of the day. Up to now, I’ve simply taken it as wanted.  

Pure Stacks as a Entire: My Opinion

General, I felt that Pure Stacks dietary supplements labored very successfully and fairly rapidly. They’re an incredible nootropics hack to have available after I must focus and be productive. Particularly after an evening of less-than-optimal sleep. The Neurofuel and Sensible Caffeine pair nicely to assist profit from the day.

The Serotonin Mind Meals can also be an incredible complement to have on the shelf for days while you’re simply “not feelin’ it.”

I really like that their substances are all-natural and backed by science. Whereas I attempted these three merchandise, they’ve others you possibly can add to your stack or experiment with. They’ve a number of different neurotransmitter-enhancing dietary supplements, together with: 

  • Acetylcholine Mind Meals – For higher consideration to element, sooner pondering, and psychological readability. 
  • GABA Mind Meals – For a peaceful thoughts, clear ideas, relaxed physique, and deeper, extra restorative sleep.
  • Dopamine Mind Meals – For laser focus, unbeatable drive to get issues achieved, higher athletic steadiness, and higher psychological readability.

Additionally they have magnesium, curcumin, krill oil, probiotics, and Vitamin D3  dietary supplements. There’s even a drink combine to assist sleep and intestine well being all of sudden. For those who’re undecided what to attempt first, you possibly can order one in every of their stacks, which mix two to 4 dietary supplements in a package. 

They even can help you construct your personal stack. Simply select a product from every of three classes: Neurotransmitter Assist, Psychological Efficiency, and Day by day Necessities. That can routinely get you 15% off of the gathering.

I’m trying ahead to making an attempt extra of their merchandise! For those who’d like to provide Pure Stacks a attempt at a 15% low cost, click on right here to go to their web site after which put in wellnessmama15 at checkout. 

Have you ever tried nootropics merchandise earlier than? What was your expertise with them? Share with us beneath!


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  4. Owen, G. N., Parnell, H., De Bruin, E. A., & Rycroft, J. A. (2008). The mixed results of L-theanine and caffeine on cognitive efficiency and temper. Dietary neuroscience, 11(4), 193–198.
  5. Richard, D. M., Dawes, M. A., Mathias, C. W., Acheson, A., Hill-Kapturczak, N., & Dougherty, D. M. (2009). L-Tryptophan: Primary Metabolic Capabilities, Behavioral Analysis and Therapeutic Indications. Worldwide journal of tryptophan analysis : IJTR, 2, 45–60.
  6. Sanders, O., & Rajagopal, L. (2020). Phosphodiesterase Inhibitors for Alzheimer’s Illness: A Systematic Evaluate of Scientific Trials and Epidemiology with a Mechanistic Rationale. Journal of Alzheimer’s illness reviews, 4(1), 185–215. 
  7. Southwick, S. M., Vythilingam, M., & Charney, D. S. (2005). The psychobiology of melancholy and resilience to emphasize: implications for prevention and therapy. Annual evaluation of scientific psychology, 1, 255–291.
  8. Tang, L., Huang, C., Zhong, J., He, J., Guo, J., Liu, M., Xu, J. P., Wang, H. T., & Zhou, Z. Z. (2019). Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective impact. European journal of medicinal chemistry, 168, 221–231.
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